Archive Dec 2012

We have collected a selection of the latest research to help keep you up to date with developments in the field of prostate cancer.

Research articles published in December 2012:

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Risk

E Kharazmi, M Fallah, K Sundquist et al.

Familial risk of early and late onset cancer: nationwide prospective cohort study

BMJ. 2012; 345

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Genetics

Personalized PSA Testing Using Genetic Variants May Reduce Unnecessary Prostate Biopsies

Helfand BT, Loeb S, Hu Q et al.

J Urol. 2012. Advanced online publication

Identification of genetic risk associated with prostate cancer using ancestry informative markers

Ricks-Santi LJ, Apprey V, Mason T et al.

Prostate Cancer Prostatic Dis. 2012; 15(4):359-64.

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Diagnosis

Multiparametric magnetic resonance imaging and ultrasound fusion biopsy detect prostate cancer in patients with prior negative transrectal ultrasound biopsies

Vourganti S, Rastinehad A, Yerram NK et al.

J Urol 2012; 188(6):2152-7

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Treatment

Population-based 10-year oncologic outcomes after low-dose-rate brachytherapy for low-risk and intermediate-risk prostate cancer

Morris Wj, Keyes M, Spadinger I et al.

Cancer. 2012. Advanced online publication.

Comparisons of the Perioperative, Functional, and Oncologic Outcomes After Robot-Assisted Versus Pure Extraperitoneal Laparoscopic Radical Prostatectomy

Ploussard G, de la Taille A, Moulin M et al.

Eur Urol. 2012. Advanced online publication.

Interaction of adjuvant androgen deprivation therapy with patient comorbidity status on overall survival after radical prostatectomy for high-risk prostate cancer

Linder BJ, Boorjian SA, Umbreit EC et al.

Int J Urol. 2012. Advanced online publication.

Stereotactic body radiation therapy for prostate cancer: Is the technology ready to be the standard of care?

Zaorsky NG, Studenski MT, Dicker AP et al.

Cancer Treat Rev. 2012. Advanced online publication.

Metformin and Prostate Cancer: Benefit for Development of Castration-resistant Disease and Prostate Cancer Mortality

Spratt DE, Zhang C, Zumsteg ZS et al.

European Urology. 2012. Advanced online publication.

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Side effects

A Phase 3, Placebo-Controlled Study of the Safety and Efficacy of Avanafil for the Treatment of Erectile Dysfunction Following Nerve-Sparing Radical Prostatectomy

Mulhall JP, Burnett AL, Wang R et al.

The Journal of Urology. 2012.Advanced online publication.

Patient-reported quality of life during radiation treatment for localized prostate cancer: results from a prospective phase II trial (pages 1690-1695)

Chen RC, Zhang Y, Chen MH et al.

BJU Int. 2012; 110(11):1690-5.

Comparison of efficacy and satisfaction profile, between penile prosthesis implantation and oral PDE5 inhibitor Tadalafil therapy, in men with nerve-sparing radical prostatectomy erectile dysfunction

Megas G, Papdopolous G, Stathouros G et al.

BJU Int. 2012. Advanced online publication.

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Recurrence

Prognostic implications of partial sampling of radical prostatectomy specimens: comparison of three methods

Iremashvili V, Lokeshwar SD, Jorda M et al.

J Urol. 2012. Advanced online publication.

External Validation of the Updated Nomogram Predicting Lymph Node Invasion in Patients with Prostate Cancer Undergoing Extended Pelvic Lymph Node Dissection

Gacci M, Schiavina R, Lanciotti M et al.

Urol Int. 2012. Advanced online publication.

Standard and saturation transrectal prostate biopsy techniques are equally accurate among prostate cancer active surveillance candidates

Linder BJ, Frank I, Umbreit EC et al.

Int J Urol. 2012. Advanced online publication.

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Advanced prostate cancer

Androgen deprivation therapy in advanced prostate cancer: is intermittent therapy the new standard of care?

Klotz L. Toren P

Curr Oncol. 2012; 19(Suppl 3):S13-21.

Targeted "bone-seeking" radiopharmaceuticals for palliative treatment of bone metastases: a systematic review and meta-analysis

D'angelo G, Sciuto R, Salvatori M et al.

Q J Nucl Med Mol Imaging. 2012; 56(6):538-43.

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Survival

Evaluating prostate cancer mortality and competing risks of death in patients with localized prostate cancer using a comprehensive nomogram

A Kutikov, M R Cooperberg, A T Paciorek et al.

Prostate Cancer Prostatic Dis. 2012; 15(4):374-379