Locally advanced prostate cancer

Locally advanced prostate cancer is cancer that is starting to break out of the prostate, or has spread to the area just outside the prostate.

Treatment options will depend on how far the cancer has spread and they either aim to get rid of the cancer or to control it long term.

If you would like to discuss your options, you can call our Specialist Nurses.

See a list of treatments for locally advanced prostate cancer.

Choosing a treatment

If you have a choice of treatments, you might like to discuss some of the following things with your doctor or nurse:

  • what the treatment involves, the pros and cons and the possible side effects
  • your general health and age, for example, if you have any other medical conditions such as heart disease
  • any clinical trials that might be available.

Treatments for locally advanced prostate cancer

External beam radiotherapy

External beam radiotherapy uses high energy X-ray beams to treat prostate cancer. The X-ray beams damage the cancer cells and stop them growing. You may have external beam radiotherapy on its own, or alongside permanent seed brachytherapy or temporary brachytherapy (internal radiotherapy). Or you might have it after surgery.

Find out more about External beam radiotherapy

Hormone therapy

Hormone therapy helps control prostate cancer by stopping the hormone testosterone from reaching the prostate cancer cells. It does not cure cancer but can keep it under control, sometimes for several years. It can also help to manage symptoms. You might have hormone therapy on its own, or with other treatments such as radiotherapy or brachytherapy.

Find out more about Hormone therapy

Temporary brachytherapy

Temporary brachytherapy involves inserting a source of high dose-rate radiation into the prostate gland for a few minutes at a time to destroy cancer cells. This is also called high dose rate brachytherapy. You may have this treatment on its own or you together with external beam radiotherapy or hormone therapy.

Find out more about Temporary brachytherapy

Clinical trials

If you have prostate cancer, you might have the chance to take part in a clinical trial. A clinical trial is a type of medical research. It aims to find new and improved ways of preventing, diagnosing, treating and controlling illnesses. Clinical trials test medicines, medical procedures or medical equipment. People are involved in a controlled and carefully planned way. This is the best way of finding out whether a new treatment is better than the current standard treatment.

Find out more about Clinical trials