In a nutshell
The aim of this project is to develop a new treatment for
advanced prostate cancer. The scientists are developing a DNA
vaccine in a protective coat, which can be applied as a patch to
the skin for painless and efficient delivery.
Why we funded it
Advanced prostate cancer is very difficult to treat and as yet
there are few treatment options. This project proposes a new DNA
vaccine, a specific sequence of DNA that makes the same protein
that is expressed on the surface of cancer cells. This
triggers the body's immune response against the 'foreign'
vaccine-produced protein, and also the cancer cells where the same
protein is expressed. Scientists hope that this strategy may go
some way towards filling the treatment gap. Previous studies have
shown that DNA vaccines are an effective way of stimulating the
body's own immune response to fight cancer.
Read a more detailed summary of this project here.